A patient is prescribed a calcium channel blocker to treat primary hypertension. Which fruit to advice?

Admin June 5, 2018
A patient is prescribed a calcium channel blocker to treat primary hypertension. Which fruit to advice?

1, Mr . Jame, 58 year old patient is prescribed a calcium channel blocker to treat primary hypertension. When you teach the patient about the medication, which of these foods will advise the patient to avoid?

  1. Grapefruit
  2. Milk
  3. Eggs
  4. Bananas.

    Answer :

  1. Grapefruit

Grapefruit and its juice contain furanocoumarins, which block the enzyme cytochrome P450 enzyme CYP3A4, which is involved in metabolizing many drugs, including calcium channel blockers. Medication blood levels can increase, becoming toxic. The levels of calcium channel blockers are increased when grapefruit or grapefruit juice is consumed, potentially causing hypotension. Grapefruit can interfere with other drugs, as well, including statins (atorvastatin, lovastatin, simvastatin), some antibiotics, and some cancer drugs.

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